The "overryding"overriding objective" of the positivism paradigm is to "prove or disprove hypotheses and ultimately to establish universal laws of behaviour through the use of numerically defined and quantifiable measures analogous to those used by the natural sciences"
Conclusions taken for one single individual cannot always be translated to aggregate terms (multiple individuals). This means that microeconomic results are not necessarily transferable to macro terms, and this can create disagreement among economists. PrestonPeston (1959) makes a good overview of the problem in the first page, or check the wikipedia page.
Economics research is highly vulnerable to bias. Even if methodologically the studies can be well grounded in logic and data, the point of view of the researcher can be influenced by one's own ideology or by political influence. A
A recent study on 159 economic literatures found "half of the research areas have nearly 90% of their results under‐powered" and "nearly 80% of the reported effects in these empirical economics literatures are exaggerated"(Ioannidis, Stanley, Doucouliagos 2017)